What is Retatrutide?
Retatrutide is a novel synthetic peptide that acts as a triple receptor agonist targeting GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors. It represents a new generation of investigational peptides designed to simulate natural hormonal responses involved in glucose metabolism, appetite suppression, and energy balance.
This compound has gained significant attention in preclinical and early clinical research due to its promising effects on body weight reduction, insulin sensitivity improvement, and lipid profile enhancement.
Mechanism of Action Peptide Sciences Retatrutide
Retatrutide binds and activates three key receptors involved in metabolic regulation:
GIP Receptor Agonism: Enhances insulin secretion and promotes nutrient storage
GLP-1 Receptor Agonism: Reduces appetite, delays gastric emptying, and supports glucose control
Glucagon Receptor Agonism: Increases energy expenditure and fat oxidation
This multi-target synergy mimics physiological hormone cascades, offering superior therapeutic potential compared to single-receptor agents.
Key Research Applications
Obesity and weight management models
Insulin resistance and Type 2 diabetes research
Lipid metabolism and liver health
Hormonal appetite regulation studies
Comparative peptide therapy evaluations
Laboratory Use Only of Peptide Sciences Retatrutide
Retatrutide 12mg is supplied as a sterile, lyophilized peptide powder, intended strictly for in vitro or laboratory research use. It is not for human consumption, diagnostic use, or therapeutic purposes.
Product Specifications
Compound Name: Retatrutide
Molecular Formula: C₁₈₁H₂₇₇N₄₇O₅₅
Molecular Weight: ~4020.5 g/mol
Purity: ≥99% (HPLC verified)
Appearance: White lyophilized powder
Quantity: 12mg per vial
Storage: Store at -20°C; protect from light and moisture
Contraindications & Handling Warnings
For licensed research institutions and professionals only
Do not inject or consume under any circumstances
Avoid contact with skin, eyes, or mucous membranes
Use appropriate PPE (personal protective equipment) when handling
Dispose of unused material in compliance with local regulations
Quality Assurance
Produced in a cGMP-compliant facility in the USA
Subjected to independent laboratory testing for identity, potency, and purity
Certificate of Analysis (CoA) available upon request for research verification
FDA Disclaimer
This product is not approved by the United States Food and Drug Administration (FDA). It is not intended to diagnose, treat, cure, or prevent any disease. It is strictly for research purposes only. Always consult regulatory guidelines before handling investigational peptides.
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