Thorne 5-MTHF | Active Folate for Methylation Support
For individuals seeking a highly bioavailable folate supplement, Thorne’s 5-MTHF provides the active, methylated form your body can use directly. This supplement is a breakthrough for those who need support for healthy methylation, a fundamental process that impacts cardiovascular health, nerve function, and mood. It’s a foundational nutrient, delivered with the purity and potency that practitioners and professional athletes trust.
Trusted by Professionals, Certified for Champions
Thorne is the brand of choice for those who leave nothing to chance. Our commitment to quality is validated by the most demanding organizations in the world.
- #1 Recommended Brand: Thorne is the clinical brand most recommended by healthcare practitioners.
- Trusted by Champions: Chosen by 100+ professional sports teams and multiple U.S. National Teams.
- NSF Certified for Sport®: This product is independently tested and certified to be free from over 200 substances banned by major athletic organizations.
“Methylation is a cornerstone of health, and many individuals have genetic variations, like in the MTHFR gene, that make converting standard folic acid difficult. Providing folate in its active L-5-MTHF form bypasses this step entirely. Thorne’s 5-MTHF is a product I trust due to its purity, NSF certification, and clinical reliability for supporting methylation pathways.”
Why L-5-Methyltetrahydrofolate? The Active Form of Folate
Standard folic acid found in many supplements must be converted by the body into its active form, 5-MTHF, before it can be used. This conversion process can be inefficient for many individuals. Thorne’s 5-MTHF provides this active form directly, ensuring optimal bioavailability and function, regardless of genetic variations. To learn more about this, you can read about the role of the MTHFR gene in processing folate from MedlinePlus Genetics.
Optimal Support for Homocysteine Metabolism
One of the most vital roles of 5-MTHF is its function as a nutritional cofactor in the metabolism of homocysteine. Maintaining healthy homocysteine levels is a well-established marker for cardiovascular health. By providing the necessary raw material for this process, 5-MTHF plays a key role in supporting healthy blood vessel function and overall cardiac wellness.
How to Use
Take one (1) capsule one to three times daily, or as recommended by your health-care practitioner. This product can be taken with or without food.
Important Safety Information
This product is not intended for children. If you are pregnant or nursing, consult your health-care practitioner before using this product. Do not exceed the recommended dose. Tamper Evident: Use only if bottle is sealed. Store tightly sealed in a cool, dry place.
Frequently Asked Questions (FAQ)
What is methylation?
Methylation is a fundamental biochemical process that happens billions of times per second in nearly every cell of your body. It’s crucial for DNA repair, detoxification, energy production, mood regulation, and controlling inflammation.
How is 5-MTHF different from folic acid?
Folic acid is a synthetic form of folate that requires a multi-step conversion process in the body to become active. 5-MTHF is the natural, active form of folate that the body can use immediately, without conversion.
Who might benefit from an active folate supplement?
Individuals with certain common genetic variations in the MTHFR gene, or those looking for direct support for methylation and homocysteine metabolism, may benefit from taking the active form of folate. A health-care practitioner
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