Mucinex Maximum Strength Day & Night Cold and Flu Medicine
When you’re fighting severe cold and flu symptoms, you need powerful relief around the clock. The Mucinex Maximum Strength Fast-Max Cold & Flu and Nightshift combo pack provides a two-part solution to help you manage your symptoms during the day and get the rest you need at night. This all-in-one liquid medicine tackles headache, fever, cough, congestion, and more.
FDA Regulated Medicine: Use as Directed
- ✅ FDA Regulated: This is an Over-The-Counter (OTC) medicine. Always read and follow the Drug Facts label.
- ✅ Pharmacist Recommended: Contains active ingredients trusted by pharmacists for multi-symptom relief.
- ✅ Targeted Formulas: Separate, targeted formulas for the symptoms that bother you most, day or night.
Daytime Relief: Fast-Max Cold & Flu
The non-drowsy daytime formula is designed to relieve your toughest symptoms without making you sleepy. It works to control your cough, break up chest congestion, reduce fever, and relieve nasal congestion and headaches, so you can feel more like yourself during the day.
Relieves: Headache, Fever, Sore Throat, Cough, Chest Congestion, Nasal Congestion.
Nighttime Relief: Nightshift Cold & Flu
The night formula is designed to relieve your worst symptoms to help you get to sleep. It reduces fever, controls cough, and relieves headache and nasal congestion, while also addressing sneezing and runny nose with an antihistamine.
Relieves: Headache, Fever, Sore Throat, Cough, Nasal Congestion, Runny Nose & Sneezing.
Active Ingredients (in each 20 mL dose)
Fast-Max (Day)
- Acetaminophen 650 mg (Pain reliever/fever reducer)
- Dextromethorphan HBr 20 mg (Cough suppressant)
- Guaifenesin 400 mg (Expectorant)
- Phenylephrine HCl 10 mg (Nasal decongestant)
Nightshift (Night)
- Acetaminophen 650 mg (Pain reliever/fever reducer)
- Dextromethorphan HBr 20 mg (Cough suppressant)
- Phenylephrine HCl 10 mg (Nasal decongestant)
- Triprolidine HCl 2.5 mg (Antihistamine)
For complete product information, please view the complete Drug Facts label on DailyMed (National Library of Medicine).
Pharmacist’s Note
“This combination pack is a common recommendation for patients seeking comprehensive management of severe cold and flu symptoms. The daytime formula addresses key symptoms like cough and congestion without causing drowsiness, while the addition of an antihistamine (Triprolidine) in the night formula effectively manages runny nose and sneezing to aid sleep. It is critical for patients to be aware of the Acetaminophen content and avoid taking other medications containing it to prevent overdose. Always dose accurately with the provided cup.”
— Dr. Ahmed Hassan, RPh, Pharm.D., Registered Pharmacist (view bio)
Directions
- Do not take the Day and Night medicines at the same time.
- Do not take more than 6 doses in total in any 24-hour period.
- Adults and children 12 years and older: 20 mL in dosing cup every 4 hours.
- Children under 12 years of age: DO NOT USE.
Important Safety Information
Warnings
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take:
- more than 6 doses in 24 hours, which is the maximum daily amount
- with other drugs containing acetaminophen
- 3 or more alcoholic drinks every day while using this product
Do not use with any other drug containing acetaminophen (prescription or nonprescription) or if you are now taking a prescription monoamine oxidase inhibitor (MAOI). Read the product label for a full list of warnings and drug interactions before use.
Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Frequently Asked Questions (FAQ)
What is the main difference between the Day and Night formulas?
The Day formula contains Guaifenesin, an expectorant to help clear chest congestion. The Night formula does not contain Guaifenesin but includes Triprolidine HCl, an antihistamine that helps with runny nose and sneezing and can cause drowsiness, which may help you rest.
Can I take Mucinex Fast-Max and Nightshift at the same time?
No. Do not take both medicines at the same time. You should only take one at a time, allowing at least 4 hours between doses. Do not exceed a total of 6 doses of either product in a 24-hour period.
Why is the liver warning for Acetaminophen so important?
Acetaminophen is a safe and effective medicine when used as directed, but taking too much can lead to severe, irreversible liver damage. It is found in many different OTC and prescription medicines, so it’s crucial to read all labels to avoid accidentally taking too much.
Disclaimer:
This is an Over-The-Counter (OTC) drug. Always read and follow the entire Drug Facts label before use. Consult a doctor or pharmacist with any questions.
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